The US PGA Championship scheduled for May 14-17 has been postponed over coronavirus concerns, the PGA of America announced on Tuesday.
It said it hoped to reschedule the event for the American summer.
The PGA Tour, a separate body which runs the game's biggest weekly circuit, has cancelled its schedule until at least May 10.
The US PGA Championship, one of the sport's four men's majors, was due to be held at TPC Harding Park in San Francisco.
"Throughout our evaluation process, we have been committed to following the guidance of public health authorities and given the coronavirus shelter-in-place order in effect in San Francisco, postponement is the best decision for all involved," said PGA of America CEO Seth Waugh.
"We are and have been working in concert with (PGA Tour) commissioner Jay Monahan and our partners and friends at the PGA Tour to find an alternative date that works for all.
"We are all very hopeful for a great outcome … and look forward to hopefully (playing the event) at a date this summer when it is once again safe and responsible to do so."
“We look forward to hopefully bringing the 2020 PGA Championship to TPC Harding Park at a date this summer when it is once again safe and responsible to do so.” – Seth Waugh
The news follows a previous announcement by Augusta National that it had postponed the Masters, the first major of the year that had been scheduled for April 9-12.
Augusta National offered no hint as to when it planned to play the tournament, though October looms as the most likely time if the coronavirus has subsided.
With the first two majors postponed, the focus turns to the June 18-21 US Open at Winged Foot in New York and the July 16-19 Open Championship at Royal St. George's in Kent, both of which for now are still on schedule.
The US Open, however, on Tuesday cancelled the first qualifying stage for an event that usually receives about 9,000 entries.
Meanwhile, news that the PGA Tour will shut down until at least May 10 means that nine non-major events have been scrapped, starting with last week's US$15 million Players Championship, which was called off after one round.