DeChambeau has only made two starts in official PGA Tour events this season.

He withdrew from the Sony Open in Hawaii with a sore left wrist, was apparently bothered by the same hand as he missed the cut at the Farmers Insurance Open and then withdrew from the Saudi International on the Asian Tour earlier this month after the opening round.

"I am very disappointed to miss the (Genesis Invitational) this week at one of my favourite golf courses on Tour," DeChambeau wrote Monday on Twitter.

"I am currently in the process of rehabbing a hip and hand injury, which I am making positive progress on day by day.

"Any news regarding my health or playing schedule will come directly from me and my team only." - Bryson DeChambeau.

"There are many false reports going around by the media that are completely inaccurate.

"Any news regarding my health or playing schedule will come directly from me and my team only.

"This is just another inaccurate report. I look forward to getting healthy and seeing everyone soon!"

The one-time major champion likely was referring to speculation that he'd signed with a controversial start-up golf league, the so-called Super Golf League, and was no longer able to compete on the PGA Tour as a consequence.

One unconfirmed report this month said DeChambeau had been offered $135 million ($A189m) to join the Saudi-backed league, which has yet to actually launch but would be spearheaded by Australian Greg Norman.

After withdrawing from the Saudi International, DeChambeau said he injured himself by slipping and falling, not because of excessive workouts as he chased inflated clubhead speed.

"Everyone needs to chill," he wrote then.

DeChambeau has slipped to No.12 in the world after starting the new year ranked eighth.

His last tournament victory came in March 2021 at the Arnold Palmer Invitational.