The former U.S Open champion's 12-under performance in White Sulfur Springs, West Virginia, was the first round under 60 so far recorded in the two-year history of the fledgling league.

He won $US4 million ($A6.1 million) for his effort as he finished with a 23-under-par total of 187 for the tournament, topping second-place finisher Mito Pereira (63) by six shots.

Matthew Wolff had fired a 61 on the par-70 layout on Friday at the Old White course, tying Harold Varner III for the lowest score in LIV's brief history.

But DeChambeau obliterated the mark on Sunday with no less than 13 birdies.

He had seven on the first nine holes, combined with a bogey on the par-3 8th, then six more on the back nine, closing his round with four consecutive birdies.

It certainly was enough for U.S Ryder Cup skipper Zach Johnson to take notice as he prepares to make his captain's picks for his team later this summer.

LIV players do not earn points towards automatic qualification for the Ryder Cup, which begins on September 29 at Marco Simone Golf and Country Club in Rome.

"I'm playing really well. I've got some equipment that's performing quite nicely off the driver, and that's a deadly combination with my putting," DeChambeau said.

"So clearly I putted well, drove it well, wedged it pretty well. You couldn't have written it up better than this.

"But if I do get a call, that would be awesome. If not, I'll be rooting them on over in Rome."

Richard Bland of England (65), Spain's David Puig (66) and Wolff (66) all finished at 16-under for the tournament, with Varner two shots behind them.

"So clearly I putted well, drove it well, wedged it pretty well. You couldn't have written it up better than this."- Bryson Dechambeau.

Australia's Cam Smith, Marc Leishman and Matt Jones were all left in a tie for 32nd position after they ended the tournament on six-under-par.

After his second-round 64, Smith couldn't get into gear, finishing with a 71.