Jarrod Lyle will make his return to professional golf at the Australian Masters in November – just 21 months after beginning a second fight to beat leukaemia.

After nearly 16 months of treatment including chemotherapy and a bone marrow transplant, the 31-year-old was given the all clear by specialists last month and he has started training and hitting practice balls in a bid to make it back to the US PGA Tour at some stage in 2014.

When you consider last November he was uncertain whether he would ever play golf again, his comeback to be in the field at Royal Melbourne later this year is remarkable.

“The fact that it is at Royal Melbourne … there’s lots of good memories there,” Lyle told Golf Australia. “I haven’t played there since 2005 at the Heineken so I’m really looking forward to it.”

Lyle says he has no doubt standing on the 1st tee waiting to hit his opening shot at Royal Melbourne it will hard not to be emotional.

“There might be a tear,” he said. “But for the rest of the time I’m sure there will plenty of smiles.

“It’s my opportunity to say thank you to everyone, including all those people I’ll probably never meet, for their support. I received so many letters and emails when I got sick and this is my way of saying thank you.”

Lyle in action during the 2012 Northern Trust Open where he finished fourth, just weeks before being diagnosed with leukaemia for the second time.PHOTO: GETTY IMAGES

But the biggest thank you will be for Bri, Jarrod’s wife, and 17-month-old, Lusi, who has been his inspiration during his fight against leukaemia for a second time.

Lyle won the hearts of a nation that week as the smiling, smooth swinging big man who finished just behind eventual winner Craig Parry and Nick O’Hern. Back then he was trying to establish his professional career having beaten acute myeloid leukaemia five years earlier.

Since then he has climbed the ranks to join the PGA Tour and has a medical exemption to rejoin the Tour when he is ready to play.

* For the full story of Jarrod Lyle’s fight and comeback to the professional ranks, read Brendan James’ interview with him in the September issue of Golf Australia, on sale on August 28